Testing for COVID-19 appears to have bogged down as turnaround time for results in some places reaches more than seven days.
Earlier in the pandemic turnaround times were up to a mere 48 hours.
Dr. Dale Bratzler, chief quality officer at OU Medicine, said there has been a “fairly drastic increase” in the number of tests being done during the last several weeks.
“Some of the reference labs, particularly those that send testing out of state, have had some challenges, and some have had delays of seven to 10 days,” Bratzler said during a virtual briefing for the media on Wednesday.
“There are spots in the state where it looks like the delay from the day the test is taken to when the result comes out has gone out longer, and that likely reflects either problems with personnel or the actual reagents you need to run the tests.”
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In May, about 6,500 specimens were collected per week. In June, it was about 6,800 specimens per week, according to Oklahoma State Department of Health data collected by the Tulsa World.
In July, an average of 12,275 COVID-19 specimens have been collected weekly.
Bratzler said weekly positivity rates for testing have fluctuated around 10%, a far cry from the low rates seen in May. There was only a 1.8% positivity rate the week of May 25.
“When you see a higher percent positive test rate, that means there is community spread of the virus,” Bratzler said. “It is true in Oklahoma now, particularly over the last few weeks, we’ve seen a fairly dramatic increase in the number of tests done, and there’s a big demand to get tests because a lot of people are calling these centers and asking to get tests done.”
And demand is likely to see another increase as schools and colleges look toward the fall semester. Oklahoma State University, the University of Tulsa and the University of Oklahoma will require students moving into dorms to be tested.
OSU will also require students moving into Greek housing to be tested, and TU will require tests of all students who plan to take in-person classes.
Some public school districts are still weighing whether to return to in-person instruction. Some have developed hybrid plans. And some have planned to head directly back to class.
“Delayed testing results can have a significant impact on our ability to isolate a patient with a positive test, and to do the appropriate contact tracing, testing, and isolation of anyone around that person who may have been exposed or infected,” Bratzler said. “To appropriately do contact tracing, you need to intervene as soon as you can after the positive test is reported.”
While public health officials have acknowledged some difficulty in acquiring reagents, the materials used to test specimens, the human component to testing could be the greater cause for delays.
Tulsa Health Department Director Bruce Dart, during a COVID-19 briefing last week, said the department and laboratories would “love to expand capacity.”
“They have to have the reagents and materials to do that, but, more importantly, we have to have the bodies to expand capacity,” Dart said. “We can get the material, but we have to have people who can actually run the test.”
Oklahoma has made significant leaps in its testing capabilities. In the early days in March, the state had only 500 test kits on hand.
As of Tuesday, medical personnel and lab technicians in the state had conducted more than 613,000 tests, and the mantra has shifted from testing only the most vulnerable populations to testing everyone, regardless of symptoms.
State Health Commissioner Lance Frye, during a COVID-19 briefing earlier this month, said the state is working to expand testing capacity.
“Our public health professionals are working around the clock to identify cases and hot spots and are responding with increased testing and support in those areas as needed,” Frye said then.
State Health Department staff and laboratory personnel meet weekly on the matter and have been discussing how to increase capacity for testing. Bratzler said labs are acquiring additional testing equipment and expanding testing site access. Additionally, federal regulators are reviewing rapid, home-based kits.
“It is possible that there will be low-cost alternatives to laboratory testing by the end of the year,” Bratzler said. “These home tests are not quite as sensitive as lab-based tests but are inexpensive enough to be done frequently.”
Video: Tulsa Mayor G.T. Bynum gives an update on the city’s COVID-19 situation.
Tulsa Mayor G.T. Bynum speaks on the city's COVID-19 situation during a July 23 press conference.
COVID-19 basics everyone needs to know as the pandemic continues.
COVID-19 basics everyone needs to know as the pandemic continues
How it spreads, who's at risk
Studies have shown many infected people show no symptoms or have symptoms so mild they may go undetected; those people can still transmit COVID-19 to About 20% of patients diagnosed with COVID-19 require hospitalization.
The disease can be fatal, especially for vulnerable populations: those older than 65, living in a nursing home or long-term care facility, and anyone with underlying health conditions such as diabetes, heart disease, lung disease or obesity.
Science of virus spread
COVID-19 is spread mainly from person to person via respiratory droplets produced by an infected person. Spread is most likely when people are in close contact, within about 6 feet. A person might also be infected with COVID-19 after touching a surface or object that has the virus on it and then touching their face. According to the CDC, evidence suggests the novel coronavirus may remain viable for hours to days on surfaces, though that form of transmission is said to be minor.
Transmission between people more than 6 feet from one another may occur in poorly ventilated and enclosed spaces, the CDC says, especially where activities cause heavier breathing, such as singing or exercising.
The infectious period for patients can begin up to 48 hours before symptom onset.
List of symptoms
The CDC recently expanded its list of possible symptoms of COVID-19. The symptoms can appear from two days to two weeks after exposure.
- Fever or chills
- Cough
- Shortness of breath or difficulty breathing
- Fatigue
- Muscle or body aches
- Headache
- New loss of taste or smell
- Sore throat
- Congestion or runny nose
- Nausea or vomiting
- Diarrhea
This list does not include all possible symptoms and will continue to be updated by the CDC. One symptom not included is "purple toes," which someone may experience with no other symptoms, sometimes several weeks after the acute phase of an infection is over. The coloration and pain is caused by a lack of blood flow to the toes caused by excessive blood clotting, a late-stage concern with COVID-19 infections.
Kinds of testing
Those getting tested may experience different kinds of swabs. The viral test, known as PCR, involves a deep nasal swab that can be painful.
Other tests that require less-invasive swabs may produce results faster, but with less accuracy. These should not be used diagnostically.
It is not yet known whether COVID-19 antibodies can protect someone being infected again or how long protection might last.
The 'serious seven'
The "serious seven" refer to close contact environments where residents should take extra precautions if they choose to attend. The seven are gyms, weddings, house gatherings, bars, funerals, faith-based activities and other small events, according to Tulsa Health Department Director Bruce Dart.
Treatments being investigated
The FDA has allowed for antiviral drug remdesivir, previously tested on humans with Ebola, to treat more severe cases of COVID-19 in adults and children. Safety and effectiveness aside, preliminary studies have shown it can shorten recovery time for some patients.
After previously approving an emergency use authorization, the FDA as of July 1 cautions against use of hydroxychloroquine or chloroquine for COVID-19 outside of the hospital setting or a clinical trial. A review of safety issues includes reports of serious heart rhythm problems and other safety issues, including blood and lymph system disorders, kidney injuries, and liver problems and failure.
Convalescent serum therapy
Some patients are receiving convalescent serum, meaning the antibodies made by people who have recovered after a COVID-19 infection. Antibody-rich blood plasma is being given to severely or critically ill COVID-19 patients, including Ascension St. John, Saint Francis Health System, OSU Center for Health Sciences and Hillcrest HealthCare System in Tulsa.
From June to July, requests for convalescent plasma from the Oklahoma Blood Institute multiplied seven-fold.
Recovery, as defined by CDC
To be considered recovered (without a test), these three things must happen, the CDC advises:
- No fever for at least 72 hours (three full days of normal temperature without the use of medicine)
- Other symptoms improved (no more cough, etc.)
- At least 10 days since symptoms first appeared






